The Neon Nurse's Charting

I don't watch all that much TV. But the other day, it occurred to me that quite a few of the ones that have caught my interest use the technique of the voiceover, which either tells us what characters are thinking (Dexter, Veronica Mars) or informs us of the moral of the story, in case we are too dim to catch on without help (Gray's Anatomy, Heroes).

What I was wondering...what if somewhere in the over-arcing TV-verse, the VO Fairy got wasted one night and mixed the voice-overs up?

It seems to me there's a lot of potential comedy gold there, fanfic-wise. I don't have the time to mess with it myself, but if anyone is looking for a new idea, help yourself!